Molecular ecosystem of ERAP in four distinct immune cell subsets from patients with ERAP-linked diseases

The aims corresponding to the research project broadly include Transcriptional regulation of ERAPs in chronic inflammation at the immune cell subset level, Proteomic regulation of ERAPs using genome-wide crispr screens, Genome/metabolome-wide toxicology study of ERAP inhibitors and Impact of ERAP2 haplotype variation in the population onTCR-repertoire.

Aroosha Raja